I did not use cream for years, also at the recommendation of my LBS I gave it a try; Butt Butter it helped with the over 50 mile rides. Ran out of that and tried Assos, even better. I cannot ride without it now. The Assos is expensive, Butt worth every penny.
Question for the girls. I am trying to get my wife into cycling and want it to be as comfortable as possible; is chamois cream recommended or not recommended?